Oral Sex With Multiple Partners Puts Men At Highest Risk Of HPV-Related Cancer
22 Октября, 2017, 13:38
"Currently available tests for the presence of oral HPV infections are not very predictive of oropharyngeal cancer risk-most people who have an oral HPV infection will eventually clear it on their own", says study co-author Gypsyamber D'Souza, PhD, an associate professor in the Bloomberg School's departments of Epidemiology and International Health.
It used the numbers of oropharyngeal cancer cases and deaths to predict the risk of cancer from oral HPV infection.
For this study, researchers analyzed data from a survey of people between the ages of 20 and 69 with the total people involved being over 13,000, and calculated how many people had oral HPV infections.
The risk was much lower among women, anyone who did not smoke, and people who had less than five oral sex partners in their lifetimes.
But the number of cases of oropharyngeal cancer is predicted to overtake cervical cancer by 2020, United States scientists warned.
Government data shows human papillomavirus, or HPV, related throat cancers have increased since the 1980's, especially among men. Oral HPV was four times more common among men who had a genital HPV infection, compared with men who did not, at 19.3% versus 4.4%. "Among men who did not smoke, cancer-causing oral HPV was rare among everyone who had less than five oral-sex partners, although the chances of having oral HPV infection did increase with number of oral sexual partners, and with smoking".
"Despite recent increases in its incidence, HPV-associated oropharyngeal cancer remains a rare cancer in the US", says co-author Carole Fakhry, MD, MPH, an associate professor in the Johns Hopkins School of Medicine and Bloomberg School's Department of Epidemiology.
It was found women who had one or no oral sex partners during their lifetimes had the lowest prevalence of oral infection with cancer-causing types of HPV, with 1.8 per cent of smokers infected, and 0.5 per cent of non-smokers.
Scientists hope to use those findings to develop screening techniques that catch the head and neck cancers but aren't burdened by cost, or the fact they would trigger needless anxiety for most people.
Men ages 50 to 59 were most likely to have an infection at 8.1 per cent of any age group. Women with 10 or more lifetime oral sex partners had a relatively low, 3.0 percent prevalence of infection, whereas for men with 10 or more lifetime oral sex partners the figure was 14.4 percent. For those who had five or more oral sex partners and also smoked, a full 15 per cent of them tested positive for the particular kind of virus.
Smoking also was associated with higher oral HPV prevalence.
Further research to explore oral HPV infection in young healthy men is now being conducted.
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